针刺穴位的组织多普勒成像研究

目的 探讨组织多普勒成像观察穴位与非穴位组织运动的可行性.方法 ①针刺30例健康志愿者双侧足三里、曲池以及外侧旁开1 cm处非穴位,在针灸针体实时受力检测系统监测下,保持进针深度和捻转力度大致相同,获取组织多普勒图像,应用组织追踪法测定针尖周围组织位移值.②针刺10例健康志愿者双侧足三里、曲池,获取得气前后组织多普勒图像,应用组织追踪法测定针尖周围组织位移值.结果 ①双侧足三里、曲池与对照非穴位处比较,穴位处平均组织位移明显较大,差异有统计学意义(P＜0.05).②得气后双侧足三里、曲池平均组织位移较得气前明显增大,差异有统计学意义(P＜0.001).结论 多普勒组织成像技术提示经穴特异性的存在,能准确检测穴位组织运动,为研究穴位局部组织的运动提供了新的思路和方法.     

A critical overview of the current myofascial pain literature – January 2018

The majority of papers included in the quarterly review discuss various aspects of dry needling (DN), which continues to be of interest to researchers and clinicians. A study by Liu et al. is the first paper to examine the effects of DN of acetylcholine, esterase and receptors. The study provides support for the integrated trigger point hypothesis and for DN. A paper by Hightower and colleagues found an intriguing link between low magnesium levels in the drink water supply, vitamin D, and myofascial pain, cancer, tendon ruptures, and colon polyps. Contributions originated in the Brazil, China, Germany, Iran, India, Poland, South Korea, Spain, Taiwan, Turkey, and the US.     

Assessment of medication adherence and treatment satisfaction in Japanese patients with psoriasis of various severities

Psoriasis is a chronic, relapsing, inflammatory keratotic skin disease. To elucidate the medication adherence and treatment satisfaction, we performed a questionnaire survey using the eight‐item Morisky Medication Adherence Scale (MMAS‐8) and nine‐item Treatment Satisfaction Questionnaire for Medication (TSQM‐9) of 163 psoriatic patients who regularly visited hospitals or clinics. To assess the relationship between the MMAS‐8/TSQM‐9 outcomes and severity of psoriasis, two different clinical severity indices were used: the Psoriasis Area and the Severity Index (PASI) for disease severity and the Psoriasis Disability Index (PDI) for quality of life (QOL) impairment. The MMAS‐8 score for oral medication was significantly higher than that for topical medication. The oral and topical MMAS‐8 scores were significantly correlated with the PDI score, but not with the PASI score, indicating that QOL impairment lowered treatment motivation. All of the TSQM‐9 domain scores (effectiveness, convenience and global satisfaction) were significantly correlated with both the PASI and PDI scores, suggesting that patients whose skin and QOL conditions were under good control had high satisfaction with treatment. Patients treated with biologics had higher satisfaction than those treated with non‐biologics.     

A MBULANCE,F IRE,AND P OLICE D ISPATCH T IMES C OMPARED WITH THE A TOMIC C LOCK

Objectives. To quantify any differences between the times used by public safety answering points (PSAPs) in a multijurisdictional county compared with the atomic clock and to determine whether there was consistency in any time differences. Methods. All 25 ambulance, fire, and police PSAPs were contacted by telephone. The current time in hours, minutes, and seconds on the dispatch center's timepiece was -requested. The atomic clock time was simultaneously recorded. Time differences between the reported and atomic clock times were calculated and the absolute values were used to calculate the mean difference. The procedure was repeated one week later. Consistency in time deviation was evaluated by subtracting the time differences between weeks 1 and 2 for each center. Results. All 25 centers were contacted and three declined to participate. Time differences ranged from ?551 to 117 seconds (mean difference: 61.2 ± 120.3) for week 1 and ?103 to 79 seconds (mean difference: 36.9 ± 33.4) for week 2. Time deviations between weeks 1 and 2 were: 0 seconds for one center, 1 to 30 seconds for 12 centers, 31 to 60 seconds for four centers, and more than 60 seconds for five centers. Conclusions. The maximum time difference between dispatch center and atomic clock times was 551 seconds. This difference may be clinically significant for time-dependent research, quality improvement tasks, or medical legal reviews when multiple PSAPs are involved. Lack of consistency in time deviation over one week suggests systematic adjustment for these differences may not be possible.     

加味八正散治疗尿路结石的临床观察

目的:观察加味八正散治疗尿路结石的临床疗效.方法:将84例尿路结石患者随机分为治疗组和对照组,每组各42例,对照组给予大量喝普通的纯净水,治疗组给予同等剂量的加味八正散治疗,10天为一个疗程,各观察两个疗程.结果:治疗组总有效率88.10%,对照组总有效率率69.05%.治疗组疗效明显优于对照组,两组比较差异具有统计学意义(P＜0.05).结论:采用加味八正散治疗尿路结石疗效明显,无明显毒副作用.     

医院制剂复方甘草口服溶液质量回顾分析

目的 对医院制剂复方甘草口服溶液进行质量回顾分析,及时发现并纠正生产过程的不良趋势,保证制剂质量.方法 采用单值-移动极差控制图法和风险级别判断矩阵对中国人民解放军联勤保障部队第九〇〇医院近五年生产的复方甘草口服溶液质量进行分析.结果 2014年6月至2019年6月,该院生产的30批次复方甘草口服溶液质量符合法定标准,控制图显示该品种生产工艺较稳定,针对复方甘草口服溶液中愈创木酚甘油醚含量波动较大的问题进行风险分析并采取了有效措施控制风险.结论 控制图分析结合风险管理,更有利于我院持续、稳定地生产出质量优异的复方甘草口服溶液.     

自拟舒郁汤联合镇静六穴治疗产后抑郁症的临床研究

目的:探讨自拟舒郁汤联合镇静六穴治疗产后抑郁症的临床效果。方法:选择2019年5月—2020年3月产后抑郁症患者60例,按照投掷硬币法分为对照组和观察组,每组30例。对照组给予盐酸帕罗西汀片治疗,观察组给予自拟舒郁汤联合“镇静六穴”治疗。比较两组患者近期疗效以及治疗前后抑郁症状、产后生活自理能力、照料婴儿能力与生活质量变化情况。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组治疗2,4,6,8周末汉密尔顿抑郁量表(HAMD-24)评分均低于对照组,差异有统计学意义(P<0.05);观察组治疗8周末产后生活自理能力评分、照料婴儿能力评分及36条简明健康状况调查表(SF-36)评分均高于对照组,差异有统计学意义(P<0.05)。结论:自拟舒郁汤联合镇静六穴治疗产后抑郁症疗效显著,可有效改善患者抑郁症状,提升产后生活自理能力、照料婴儿能力和生活质量。     

针刺肾俞五十七穴配合闪罐法治疗肝郁脾虚型肥胖并发高脂血症104例

目的 :探讨针刺肾俞穴配合闪罐法治疗肝郁脾虚型肥胖并发高脂血症的临床疗效。方法 :208例患者随机分为治疗组与对照组,每组104例,治疗组给予针刺肾俞穴配合闪罐法,对照组给予普通针刺治疗。观察两组患者治疗前后各项肥胖指标、血脂指标的变化,并统计临床疗效。结果:两组临床疗效总有效率分别为92.31%、74.04%,差异有统计学意义(P<0.05);治疗后治疗组与对照组在肥胖指标、血脂指标方面比较差异有统计学意义(P<0.05)。结论:针刺肾俞穴配合闪罐法治疗肥胖并发高脂血症具有减肥降脂双重作用,针刺肾俞穴配合闪罐法治疗肥胖并发高脂血症疗效优于普通针刺组。     

经典名方药物考证关键问题分析与要点建议

笔者对已报道的经典名方药物考证相关研究进行系统梳理与分析，总结当前研究存在的问题与不足，提出经典名方药物考证要点建议，为经典名方药物考证相关研究提供借鉴。该文分别从注意古今药物考证内涵的异同、注重多维信息的综合利用、注重药物不同关键环节历史流变的梳理与考证、注重近代学名考订沿革梳理、注重尊古不泥古的考证原则、注重文献学基础知识等角度进行探讨，提出经典名方药物考证应对本草考证的现状、问题、成果进行深入的总结分析，吸收前人的优点，补充以往考证的不足，并在此基础上根据经典名方药物考证自身特点，形成特有的研究体系，注重历史变迁的脉络梳理，注重横断面分析，在全面分析基原、道地产区、药用部位与炮制等不同关键环节历史变迁基础上，充分吸收近现代研究成果，并结合当前生产力和认知水平，给出不同时期经典名方药物的合理关键信息，为经典名方的开发奠定坚实基础。